San Diego to Callao (Lima)

Laid-back, friendly and blessed with near-perfect weather all year round, San Diego is one of America's most likeable cities. Enjoy a stroll through Balboa Park, dotted with beautiful Spanish Renaissance-style architecture, take a whale watching trip along the coast, or sample the nightlife of the trendy Gaslamp Quarter. The swells of Mission Beach and Pacific Beach attract a surfer crowd, while the Old Town has a strong Hispanic influence thanks to the city's proximity to the Mexican border. There are also plenty of family-friendly attractions, including Legoland, SeaWorld and the famous San Diego Zoo.

The sister towns of Cabo San Lucas and San José del Cabo sit at the tip of Mexico’s Baja California peninsula. The towns themselves are mostly given over to luxury hotels and boisterous nightlife, but the surrounding landscape is characterised by arid arroyos, bristly cacti and rocky coastal outcrops.

Mazatlán is one of the most popular beach resorts on the Pacific coast of Mexico, and tourists tend to congregate in the Zona Dorada, where the majority of the hotels are concentrated. The old town is much more interesting, however, with elegantly faded colonial architecture and a vibrant cultural scene.

The resort town of Puerto Vallarta, on Mexico’s Pacific coast, has bags of charm in spite of its popularity. Spend some time exploring the pretty old town, with its cobbled streets and quirky boutiques, or relax on the beach. Humpback whales breed out in the bay during the winter months, and dolphins can be spotted year round.

A cruise call at Acajutla is a rare opportunity to explore the tiny Central American nation of El Salvador. Popular excursions include the Mayan ruins at Tazumal, scuba diving off beautiful Los Cabanos beach, or a trip to the Izalco volcano, where you can peer down into the dormant caldera.

Situated on a peculiarly shaped peninsula on the Gulf of Nicoya, Puntarenas is a popular weekend beach destination for residents of Costa Rica’s capital, San José. The port itself is not pretty, but the beachfront Paseo de los Turistas is a nice place to relax with a drink or enjoy a seafood lunch.

The Ecuadorian port of Manta is known as the “tuna capital of the world”, and you’ll see plenty of fishing boats as you arrive. The beach is a popular destination for local tourists, but you may find that the nearby town of Montecristi, home of the Panama hat, makes for a more interesting excursion.

Guayaquil is Ecuador’s largest city and most important commercial centre, and acts as the gateway to the Pacific coast and the wildlife haven of the Galapagos Islands. It’s a busy, buzzing sort of place, centred around the pleasant riverfront Malecón promenade.

Salaverry is the nearest port to Trujillo, northern Peru’s most important city. Located amongst the verdant Andean foothills, Trujillo is home to a host of beautiful colonial buildings, and is also known for the spectacular nearby ruins of Chan Chan, the largest pre-Columbian city in South America.

Peru’s underrated capital enjoys a fine setting on the Pacific coast, and the handsome colonial-era buildings surrounding the Plaza de Armas give clues to Lima’s distinguished history; for three centuries this was the capital of the Spanish Americas, when the city grew rich on the back of plundered Inca gold.