Fort Lauderdale to Callao (Lima)

These days Fort Lauderdale is a sophisticated place awash with upmarket hotels and excellent restaurants. The glorious weather and swathes of golden beach are still a huge draw, but there are also plenty of cultural attractions, such as the Museum of Art and the Museum of Discovery and Science. The city also boasts 300 miles of navigable waterways and canals, meaning there's plenty of space for the resident millionaires to park their yachts, and the cruise port is one of the busiest in the world.

Cozumel first made its name as an off the beaten track destination for divers, thanks to the crystalline waters and low key beach vibe. These days the cat is very much out of the bag, but get away from the craft shops and jewellery stores of the busy port and you’ll find a welcoming island community that is still authentically Mexican.

Belize’s capital does not enjoy the best reputation, and we wouldn’t recommend spending too much time here; use it instead as a jumping-off point to explore the fascinating Mayan ruins of Xunantunich, Lamanai and Altun Ha, or take a snorkelling trip to the beautiful Barrier Reef, including the famous Blue Hole.

The port of Santo Tomás de Castilla sits on Guatemala’s sliver of Caribbean coastline, and serves as a jumping-off point to explore this fascinating country. Nearby highlights include the Mayan site of Quiriguá and colourful, laid-back Livingston, and it’s also possible to take a day trip by air to the famous ruins at Tikal.

Roatán is the largest and busiest of the Bay Islands, which sit off the coast of Honduras in the crystal clear waters of the Caribbean Sea. It’s a fantastic destination for divers and snorkellers, with a stunning reef just offshore, and also boasts some lovely beaches.

Puerto Limón is a busy port on Costa Rica’s Caribbean coast, and plays a vital role in the export of bananas. Take a trip out of the city and explore the lush rainforest, with nearby attractions including the canals of Tortuguero National Park, a key breeding site for green turtles.

Cartagena was founded by Spanish conquistadors in 1533, and the beautifully preserved centre is a real highlight of Colombia’s Caribbean coast. The walled old town, the Ciudad Amurallada, is a camera-friendly collection of cobbled streets and colourful, colonial-era buildings.

The port of Fuerte Amador sits at the southern edge of Panama City, near the Pacific entrance to the Panama Canal. The shining skyscrapers of the Panamanian capital are a testament to the city’s status as a key financial centre, while the tiny Casco Viejo is home to pretty colonial streets, hip hotels and happening bars.

The Ecuadorian port of Manta is known as the “tuna capital of the world”, and you’ll see plenty of fishing boats as you arrive. The beach is a popular destination for local tourists, but you may find that the nearby town of Montecristi, home of the Panama hat, makes for a more interesting excursion.

Guayaquil is Ecuador’s largest city and most important commercial centre, and acts as the gateway to the Pacific coast and the wildlife haven of the Galapagos Islands. It’s a busy, buzzing sort of place, centred around the pleasant riverfront Malecón promenade.

Salaverry is the nearest port to Trujillo, northern Peru’s most important city. Located amongst the verdant Andean foothills, Trujillo is home to a host of beautiful colonial buildings, and is also known for the spectacular nearby ruins of Chan Chan, the largest pre-Columbian city in South America.

Peru’s underrated capital enjoys a fine setting on the Pacific coast, and the handsome colonial-era buildings surrounding the Plaza de Armas give clues to Lima’s distinguished history; for three centuries this was the capital of the Spanish Americas, when the city grew rich on the back of plundered Inca gold.