From Panama City to Miami · South America & Antarctica · 12 nights
From Panama City to Miami
The first of two new Prestige Class vessels, Regent’s first new ship class in a decade, the brand-new Seven Seas Prestige will join the fleet in 2026.
Seven Seas Prestige will boast one of the highest crew-to-guest
ratios in the industry and feature brand new accommodation
categories and new dining experiences.
The port of Fuerte Amador sits at the southern edge of Panama City, near the Pacific entrance to the Panama Canal. The shining skyscrapers of the Panamanian capital are a testament to the city's status as a key financial centre, while the tiny Casco Viejo is home to pretty colonial streets, hip hotels and happening bars. If you find the city's chaotic traffic offputting, you may prefer an excursion to the canal's Gatún Lake in search of wildlife including capuchin monkeys and sloths.
Cartagena was founded by Spanish conquistadors in 1533, and the beautifully preserved centre is a real highlight of Colombia’s Caribbean coast. The walled old town, the Ciudad Amurallada, is a camera-friendly collection of cobbled streets and colourful, colonial-era buildings.
The tiny Dutch Caribbean island of Aruba, located just off the coast of Venezuela, lies outside of the hurricane belt, meaning it enjoys a largely dry climate, and boasts some of the best beaches in the region, if not the world.
The gabled houses of Willemstad lend an undeniably Dutch feel to the capital of little Curaçao, with a splash of Caribbean colour thrown in. The island itself is not your typical lush tropical paradise - the landscape is characterised instead by thorny shrubs and cacti - but there are some fantastic beaches and quaint little villages.
Browse the markets of charming St George’s, fragrant with the scent of cinnamon and nutmeg, and you’ll soon understand why Grenada is known as the ‘isle of spice’. This is one of the Caribbean’s most enchanting islands, fringed by gorgeous beaches and largely unsullied by mass market tourism.
The island of Dominica stands out from the rest of the Caribbean, a rugged natural paradise that remains blissfully free of mass market tourism. The capital, Roseau, is pleasant enough, but the island interior offers so much more, including thick jungle, bubbling hot springs, cascading waterfalls and abundant birdlife.
The busiest and most developed of the Virgin Islands, St. Thomas is nevertheless blessed with typically Caribbean good looks. The main town, Charlotte Amalie, is situated on a perfect natural harbour, and in its colonial heyday its warehouses were filled with indigo, tobacco and cotton.
Downtown Miami is a destination in its own right, with a host of world class galleries, but it's still Miami Beach that draws the biggest crowds. The Art Deco district around South Beach is very much back in vogue, with new restaurants, bars and luxury developments sprouting up all over the place.
