Lisbon to Piraeus

The roots of historic Lisbon's fame lie in its strategic position on the edge of the Atlantic and the fact it offers one of the world's greatest natural harbours. No surprise therefore that it became the home of the world's most famous explorers such as Vasco da Gama, Magellan and Prince Henry the Navigator. Built on seven hills, we always find Lisbon to be soulful, captivating and picturesque, with architecture which reflects its status as a great port.

Portimão is a bustling fishing port and gateway to the Algarve, with a pleasant riverside promenade where the smell of sizzling sardines fills the air. The most popular attraction is Praia da Rocha just to the south, one of the Algarve’s loveliest beaches.

After years of neglect, Tangier is finally being restored to its former glory as a cosmopolitan crossroads between Europe and Africa. The Moroccan government has invested heavily in modern infrastructure, while the spruced up medina shines with a new-found cultural dynamism.

Melilla is a post-colonial oddity, a Spanish enclave on the north coast of Morocco. The city is a fascinating blend of Spanish, Moorish and Berber influences, with an impressive collection of modernist buildings, plenty of bustling tapas bars and an atmospheric walled old town, the Medina Sidonia.

Tunisia’s capital is a whirlwind of energy, the narrow lanes of the old medina packed with people and the roads noisy with traffic. The more orderly streets of the Ville Nouvelle are home to some handsome colonial buildings, while the ruins of ancient Carthage make for a fascinating day trip.

Sardinia’s capital is a fascinating patchwork of historical architecture and vertiginous streets, crowned by the old hilltop citadel of Il Castello. Explore the island’s history at the Museo Archeologico, where you can learn about Sardinia's ancient Nuragic civilisation.

The attractive, oceanfront capital of Corsica was the birthplace of the island’s most famous son, Napoleon Bonaparte. You can find out more about the emperor at his childhood home, the Maison Bonaparte, which is now a museum.

The rumbustious port of Marseille often gets a bad press, but the city has been transformed in recent years, with a host of new cultural attractions. The vibrant Vieux Port remains at the heart of life in Marseille, however, and is the best place to begin your exploration of the city’s many historic sights.

The bustling fishing village of Palamós is one of the loveliest spots on the Costa Brava, surrounded by beautiful beaches and rugged coves. You can also use your stop here as a jumping off point for exploring nearby medieval villages, the historic city of Girona or the fantastic Salvador Dalí museum in Figueres.

From the warren-like medieval streets of the Barri Gòtic to the fantastical modernist architecture of Antoni Gaudí, from the dizzy heights of Mount Tibidabo to the golden sands of Barceloneta, there’s never a dull moment in Barcelona.

Toulon is not the sort of place you would expect to find on the Côte d’Azur, a gritty port city that’s home to France’s most important naval base. It’s not completely without charm, however, and for some travellers it may come as a breath of fresh air after the glitz of the Riviera. For the best view, take the cable car to the top of Le Faron mountain.

Renowned for its casino, its Grand Prix and its oligarch-friendly tax policies, Monte Carlo is glamour and hedonism personified, with a price tag to match. This little principality enjoys a lovely setting, the villas and penthouses tumbling down the hillside towards the sweeping blue expanse of the Mediterranean.

This tiny village on the Ligurian coast must be one of the most photographed spots in Italy, and no wonder; brightly coloured houses cling to the hillside overlooking a delightfully picturesque little harbour, where fishing boats gently bob alongside luxury yachts.

The faded port town of Livorno serves as a gateway to Tuscany’s star attractions. Wonderful Florence, the cradle of the Renaissance, is resplendent with beautiful architecture and unrivalled artistic treasures, while nearby Pisa is of course famous for its precarious Leaning Tower.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

Situated on the north eastern tip of Sicily, so close to the Italian mainland you can almost touch it, Messina is the busy main entry point to the island. The city was flattened by an earthquake in 1908, and again by Allied bombing in 1943, so few historical sights remain, although the cathedral is one of Sicily’s most impressive.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.