Civitavecchia to Athens

One of the world's great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. As the saying goes, the city wasn't built in a day, and if you want to make the most of Rome you'll need to spend at least a couple of nights here. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

Agropoli is a popular summer resort town on the Cilento coast of southern Italy, with a pleasant historic core and some interesting churches. Most visitors are lured here by the beautiful beaches of Trentova Bay, situated just to the southwest of the town.

Taormina enjoys a truly spectacular setting on Sicily’s east coast, perched on a mountainside looking out towards the smouldering Mount Etna. The medieval streets are pleasant but often crowded in high season, so we’d recommend getting out and exploring the surrounding countryside.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Nafplion is one of the most beautiful cities on the Greek mainland, situated on the Argolic Gulf overlooked by the imposing Palamidi Fortress. The narrow streets of the old town are home to a beguiling mix of Venetian, Turkish and Greek architecture, while just offshore is the little island castle of Bourtzi.

Syros is one of the smallest of the Cyclades islands, though it’s also the administrative capital of the archipelago. Not many cruise ships call here, so you’ll find the beaches are much less crowded than other islands, and the main town, Ermoupoli, is home to a fascinating mix of architectural styles.

Bodrum is one of the trendiest destinations on Turkey’s Aegean coast, with plenty of private yachts bobbing alongside the traditional gulet boats in the harbour. Whitewashed buildings draped in bougainvillea give the town a Greek feel, overlooked by the imposing 15th century crusader castle.

Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.

Glamorous Mykonos is the most popular of the Cyclades islands, well known as a haunt of the rich and the famous. It’s also the gateway to the nearby island of Delos, home to one of the most important archaeological sites in Greece.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.