San Antonio to Hamburg

Chile's cosmopolitan capital is a smart, sophisticated place, where life plays out against the backdrop of the snow-capped Andean mountains. Santiago's moneyed elite congregate in the upmarket districts of the Barrio Alto, while Centro is home to museums, theatres and shopping malls. It's a leafy and eminently liveable city, in spite of the fact that more than a third of the population of Chile lives in Santiago. The city continues to grow outwards and upwards, its skyline crowned by the Costanera Centre, South America's tallest building, but an excellent metro system makes it easy to get around, and there are several lovely parks that afford plenty of breathing space.

The busy port of Coquimbo is the gateway to the charming colonial city of La Serena, one of the oldest in Chile, where you’ll find attractive architecture and a fine stretch of beach. Other nearby sights include the fertile Elqui and Limarí Valleys, home to excellent wineries and ancient petroglyphs.

Arica sits at the northern tip of Chile, known as ‘the land of the eternal spring’ thanks to its temperate year-round climate. Sightseeing options include the War of the Pacific battlefield at El Morro and the breathtaking altiplano scenery of Lauca National Park, a stunning high-altitude landscape of snow-dusted volcanoes and shimmering lakes.

Peru’s underrated capital enjoys a fine setting on the Pacific coast, and the handsome colonial-era buildings surrounding the Plaza de Armas give clues to Lima’s distinguished history; for three centuries this was the capital of the Spanish Americas, when the city grew rich on the back of plundered Inca gold.

The Ecuadorian port of Manta is known as the “tuna capital of the world”, and you’ll see plenty of fishing boats as you arrive. The beach is a popular destination for local tourists, but you may find that the nearby town of Montecristi, home of the Panama hat, makes for a more interesting excursion.

The port of Fuerte Amador sits at the southern edge of Panama City, near the Pacific entrance to the Panama Canal. The shining skyscrapers of the Panamanian capital are a testament to the city’s status as a key financial centre, while the tiny Casco Viejo is home to pretty colonial streets, hip hotels and happening bars.

The tiny Dutch Caribbean island of Aruba, located just off the coast of Venezuela, lies outside of the hurricane belt, meaning it enjoys a largely dry climate, and boasts some of the best beaches in the region, if not the world.

These days Fort Lauderdale is a sophisticated place awash with upmarket hotels and excellent restaurants. The glorious weather and swathes of golden beach are still a huge draw, but there are also plenty of cultural attractions, such as the Museum of Art and the Museum of Discovery and Science.

Port Canaveral is the gateway to Orlando’s many attractions, including beaches, theme parks and the Kennedy Space Centre, where you can meet real astronauts. If you’re lucky you may be in port for a rocket launch, though it’s difficult to plan for as schedules are subject to weather conditions and technical hitches.

Ponta Delgada is the capital of São Miguel, the largest and most populous island of the Azores. Founded in the 15th century, the city is home to elegant architecture and some excellent restaurants, though the main attraction is the tranquility and natural beauty of the surrounding countryside.

Southampton is the UK’s leading port. Bustling modern cruise terminals, as well as wharfs and commercial harbours, line the waterfront, whilst the city itself is a fascinating mix of ancient and modern, with a picturesque old town, the original city walls still standing, and super-modern shopping centres and office complexes

Zeebrugge’s main attraction is its proximity to Bruges. This beautifully preserved old town is a magical maze of winding cobbled lanes, narrow canals and gorgeous gabled houses, and it’s no wonder so many visitors throng the streets in summer.

Known locally as ‘the gateway to the world’, the port of Hamburg has a rich maritime history. Of course the city has its seedy side, as characterised by the old red light district around the Reeperbahn, but it’s also a vibrant, progressive city with some excellent museums, galleries and theatres.